David M. Hockenbery
Professor
Head, Gastroenterology & Hepatology Section
Member, Fred Hutchinson Cancer Research Center
Seattle Cancer Care Alliance

Faculty Information

Biography

Members of Dr. Hockenbery's laboratory study the genetic and biochemical mechanisms of programmed cell death, or apoptosis, in a variety of experimental systems. Normal cell death occurring during development and following terminal differentiation has typical morphologic and biochemical features collectively termed apoptosis. The precise control of these events is obviously of great importance to the organism and many model systems have demonstrated the requirement for active RNA and protein synthesis for cell death to proceed, suggesting an internally programmed process. One regulator of this process is the bcl-2 oncogene, which blocks apoptosis in vitro and in vivo and appears to normally control the timing of cell death in many cell lineages.

Board Certifications:

  • Gastroenterology, 1989, American Board of Internal Medicine
  • Internal Medicine, 1985, American Board of Internal Medicine
Education & Training: 
Teaching Appointment
University of Washington
2012
Fellowship in Gastroenterology/Hepatology
Washington University School of Medicine
1992
Residency in Internal Medicine
Johns Hopkins University School of Medicine
1986
Internship in Internal Medicine
Johns Hopkins University School of Medicine
1985
Medical Education
Washington University School of Medicine
1982