Tatiana Khokhlova
Research Associate Professor
Medicine
Division of Gastroenterology

Faculty Information

Biography

Dr. Tatiana (Tanya) Khokhlova is an Assistant Professor of Research who specializes in ultrasound technology for cancer diagnostics and therapy.

She joined UWGI faculty as Acting Instructor in 2012 after completing her PhD in Physics from Moscow State University (Moscow, Russia) and postdoctoral training at the University of Washington. Dr. Khokhlova’s current research projects are primarily aimed at developing ultrasound-based non-invasive interventions for treatment of pancreas cancer termed pulsed focused ultrasound (pFUS) and translating these interventions and associated devices from pre-clinical studies to clinical trials. Other ongoing projects span a wide range of clinical targets, including minimally invasive evacuation of large traumatic hematomas, using ultrasound to stimulate the release of cancer biomarkers and non-invasive ablation options for benign prostate hyperplasia. This research is done in close collaboration with Center for Industrial and Medical Ultrasound (Applied Physics Lab, University of Washington).

Education & Training: 
Senior Research Fellow in Gastroenterology
University of Washington School of Medicine
Postdoctoral Fellow in Gastroenterology
University of Washington School of Medicine
MV
Lomonosov Moscow State University
PhD in Physics
Lomonosov Moscow State University
MS in Physics (Cum Laude)
Lomonosov Moscow State University
Publications
Publications: 

Ultrastructural Analysis of Volumetric Histotripsy Bio-effects in Large Human Hematomas.

Ponomarchuk EM, Rosnitskiy PB, Khokhlova TD, Buravkov SV, Tsysar SA, Karzova MM, Tumanova KD, Kunturova AV, Wang YN, Sapozhnikov OA, Trakhtman PE, Starostin NN, Khokhlova VA.
Ultrasound Med Biol. 2021 Sep;47(9):2608-2621. doi: 10.1016/j.ultrasmedbio.2021.05.002. Epub 2021 Jun 9.
PMID: 34116880
 

Partial Respiratory Motion Compensation for Abdominal Extracorporeal Boiling Histotripsy Treatments With a Robotic Arm.

Thomas GPL, Khokhlova TD, Khokhlova VA.
IEEE Trans Ultrason Ferroelectr Freq Control. 2021 Sep;68(9):2861-2870. doi: 10.1109/TUFFC.2021.3075938. Epub 2021 Aug 27.
PMID: 33905328
 

Inertial Cavitation Behaviors Induced by Nonlinear Focused Ultrasound Pulses.

Bawiec CR, Rosnitskiy PB, Peek AT, Maxwell AD, Kreider W, Haar GRT, Sapozhnikov OA, Khokhlova VA, Khokhlova TD.
IEEE Trans Ultrason Ferroelectr Freq Control. 2021 Sep;68(9):2884-2895. doi: 10.1109/TUFFC.2021.3073347. Epub 2021 Aug 27.
PMID: 33861702